Mouse Tlk1 polyclonal (C-term), anti-mouse
€0.00
In stock
SKU
AC-AP17323B
Catalog Number: AC-AP17323B
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB37154
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB37154
Applications: WB
Datasheet
Request Information
Background:
Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly (By similarity). Isoform 3 protects the cells from the ionizing radiation by faciliting the repair of DSBs. In vitro, phosphorylates histone H3 at 'Ser-10' (By similarity).
Other Names:
Serine/threonine-protein kinase tousled-like 1, Tousled-like kinase 1, Tlk1
Target/Specificity:
This Mouse Tlk1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 701-728 amino acids from the C-terminal region of mouse Tlk1.
Antigen Region:
701-728
Antigen Type: Synthetic Peptide
Gene Name: Tlk1
Gene ID: 228012
Primary Accession: Q8C0V0
NCBI Accession: NP_766252.2
Other Accession: Q9UKI8; NP_766252.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly (By similarity). Isoform 3 protects the cells from the ionizing radiation by faciliting the repair of DSBs. In vitro, phosphorylates histone H3 at 'Ser-10' (By similarity).
Other Names:
Serine/threonine-protein kinase tousled-like 1, Tousled-like kinase 1, Tlk1
Target/Specificity:
This Mouse Tlk1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 701-728 amino acids from the C-terminal region of mouse Tlk1.
Antigen Region:
701-728
Antigen Type: Synthetic Peptide
Gene Name: Tlk1
Gene ID: 228012
Primary Accession: Q8C0V0
NCBI Accession: NP_766252.2
Other Accession: Q9UKI8; NP_766252.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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