Mouse TLR2 polyclonal (C-term), anti-mouse
€0.00
In stock
SKU
AC-AP1502c
Catalog Number: AC-AP1502c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB2603
Applications: WB, IHC-P-Leica
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB2603
Applications: WB, IHC-P-Leica
Datasheet
Request Information
Background:
TLR2 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR2 is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.
Other Names:
Toll-like receptor 2, CD282, Tlr2
Target/Specificity:
This Mouse TLR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 720-749 amino acids from the C-terminal region of mouse TLR2.
Antigen Region:
720-749
Antigen Type: Synthetic Peptide
Gene Name: Tlr2
Gene ID: 24088
Primary Accession: Q9QUN7
NCBI Accession: NP_036035.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
TLR2 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR2 is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.
Other Names:
Toll-like receptor 2, CD282, Tlr2
Target/Specificity:
This Mouse TLR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 720-749 amino acids from the C-terminal region of mouse TLR2.
Antigen Region:
720-749
Antigen Type: Synthetic Peptide
Gene Name: Tlr2
Gene ID: 24088
Primary Accession: Q9QUN7
NCBI Accession: NP_036035.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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