Mouse TLR6 polyclonal (N-term), anti-human, mouse
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In stock
SKU
AC-AP1506b
Catalog Number: AC-AP1506b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB2725
Applications: WB, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB2725
Applications: WB, IHC-P
Datasheet
Request Information
Background:
TLR6, a Type I membrane protein that belongs to the Toll-like rceptor family, participates in the innate immune response to Gram-positive bacteria and fungi. It acts via MyD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. The protein recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2. It binds to TLR2 via their respective extracellular domains, and to MyD88 via their respective TIR domains. TLR6 is detected in monocytes, CD11c+ immature dendritic cells, plasmacytoid pre-dendritic cells and dermal microvessel endothelial cells.
Other Names:
Toll-like receptor 6, CD286, Tlr6
Target/Specificity:
This Mouse TLR6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of mouse TLR6.
Antigen Region:
1-30
Antigen Type: Synthetic Peptide
Gene Name: Tlr6
Gene ID: 21899
Primary Accession: Q9EPW9
NCBI Accession: NP_035734.3
Other Accession: NP_035734
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
TLR6, a Type I membrane protein that belongs to the Toll-like rceptor family, participates in the innate immune response to Gram-positive bacteria and fungi. It acts via MyD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. The protein recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2. It binds to TLR2 via their respective extracellular domains, and to MyD88 via their respective TIR domains. TLR6 is detected in monocytes, CD11c+ immature dendritic cells, plasmacytoid pre-dendritic cells and dermal microvessel endothelial cells.
Other Names:
Toll-like receptor 6, CD286, Tlr6
Target/Specificity:
This Mouse TLR6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of mouse TLR6.
Antigen Region:
1-30
Antigen Type: Synthetic Peptide
Gene Name: Tlr6
Gene ID: 21899
Primary Accession: Q9EPW9
NCBI Accession: NP_035734.3
Other Accession: NP_035734
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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