Mouse TLR8 polyclonal (C-term), anti-mouse
€0.00
In stock
SKU
AC-AP1508d
Catalog Number: AC-AP1508d
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB2787
Applications: WB, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB2787
Applications: WB, IHC-P
Datasheet
Request Information
Background:
TLR8 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR8 is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.
Other Names:
Toll-like receptor 8, CD288, Tlr8
Target/Specificity:
This Mouse TLR8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 957-987 amino acids from the C-terminal region of mouse TLR8.
Antigen Region:
957-987
Antigen Type: Synthetic Peptide
Gene Name: Tlr8
Gene ID: 170744
Primary Accession: P58682
NCBI Accession: NP_573475.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
TLR8 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR8 is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.
Other Names:
Toll-like receptor 8, CD288, Tlr8
Target/Specificity:
This Mouse TLR8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 957-987 amino acids from the C-terminal region of mouse TLR8.
Antigen Region:
957-987
Antigen Type: Synthetic Peptide
Gene Name: Tlr8
Gene ID: 170744
Primary Accession: P58682
NCBI Accession: NP_573475.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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