Mouse Trib3 Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP14299b
Background:
Trib3 disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the 'Thr-308' phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity. Interacts with MAPK kinases and regulates activation of MAP kinases. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells. Does not display kinase activity.
Other Names:
Tribbles homolog 3, TRB-3, Neuronal cell death-inducible putative kinase, Trib3, Nipk, Trb3
Gene Name: Trib3
Gene ID: 228775
Primary Accession: Q8K4K2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Trib3 disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the 'Thr-308' phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity. Interacts with MAPK kinases and regulates activation of MAP kinases. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells. Does not display kinase activity.
Other Names:
Tribbles homolog 3, TRB-3, Neuronal cell death-inducible putative kinase, Trib3, Nipk, Trb3
Gene Name: Trib3
Gene ID: 228775
Primary Accession: Q8K4K2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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