Mouse TSC1 Blocking Peptide (Center T515)
€363.00
In stock
SKU
AC-BP19826c
Background:
In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
Other Names:
Hamartin, Tuberous sclerosis 1 protein homolog, Tsc1, Kiaa0243
Target/Specificity:
The synthetic peptide sequence is selected from aa 509-523 of MOUSE Tsc1
Gene Name: Tsc1 {ECO:0000303|PubMed:11130985, ECO:0000312|MGI:MGI:1929183}
Gene ID: 64930
Primary Accession: Q9EP53
Other Accession: Q9Z136; NP_075025.2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
Other Names:
Hamartin, Tuberous sclerosis 1 protein homolog, Tsc1, Kiaa0243
Target/Specificity:
The synthetic peptide sequence is selected from aa 509-523 of MOUSE Tsc1
Gene Name: Tsc1 {ECO:0000303|PubMed:11130985, ECO:0000312|MGI:MGI:1929183}
Gene ID: 64930
Primary Accession: Q9EP53
Other Accession: Q9Z136; NP_075025.2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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