Mouse TUG (clone 4A11A6G11), anti-mouse
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In stock
SKU
BT-MCA3207
Catalog Number: BT-MCA3207
Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity: mouse
Application(s): WB
Datasheet
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Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity: mouse
Application(s): WB
Datasheet
Request Information
Background:
The TUG protein contains a UBX domain, for GLUT4. In truncated form, TUG acts in a dominant-negative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes, this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes, and is not mobilized to the plasma membrane by insulin.
Research Area: Others
Synonyms: ASPCR1, ASPL, ASPS, RCC17, TUG, UBXD9, UBXN9
Immunogen: Purified recombinant fragment of TUG expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
Storage:
4°C|-20°C for long term storage
The TUG protein contains a UBX domain, for GLUT4. In truncated form, TUG acts in a dominant-negative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes, this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes, and is not mobilized to the plasma membrane by insulin.
Research Area: Others
Synonyms: ASPCR1, ASPL, ASPS, RCC17, TUG, UBXD9, UBXN9
Immunogen: Purified recombinant fragment of TUG expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
Storage:
4°C|-20°C for long term storage
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