Mouse Txnip Blocking Peptide (Center)
€363.00
In stock
SKU
AC-BP20130c
Background:
May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells.
Other Names:
Thioredoxin-interacting protein, Vitamin D3 up-regulated protein 1, Txnip, Vdup1
Target/Specificity:
The synthetic peptide sequence is selected from aa 131-145 of MOUSE Txnip
Gene Name: Txnip
Gene ID: 56338
Primary Accession: Q8BG60
Other Accession: Q5M7W1; NP_001009935.1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells.
Other Names:
Thioredoxin-interacting protein, Vitamin D3 up-regulated protein 1, Txnip, Vdup1
Target/Specificity:
The synthetic peptide sequence is selected from aa 131-145 of MOUSE Txnip
Gene Name: Txnip
Gene ID: 56338
Primary Accession: Q8BG60
Other Accession: Q5M7W1; NP_001009935.1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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