Mouse Txnip polyclonal (Center), anti-mouse
€0.00
In stock
SKU
AC-AP20130c
Catalog Number: AC-AP20130c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB30652
Applications: IHC-P, WB
Datasheet
Request Information
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB30652
Applications: IHC-P, WB
Datasheet
Request Information
Background:
May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells.
Other Names:
Thioredoxin-interacting protein, Vitamin D3 up-regulated protein 1, Txnip, Vdup1
Target/Specificity:
This Mouse Txnip antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-145 amino acids from the Central region of mouse Txnip.
Antigen Region:
116-145
Antigen Type: Synthetic Peptide
Gene Name: Txnip
Gene ID: 56338
Primary Accession: Q8BG60
NCBI Accession: NP_001009935.1;NP_076208.2
Other Accession: Q5M7W1; NP_001009935.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells.
Other Names:
Thioredoxin-interacting protein, Vitamin D3 up-regulated protein 1, Txnip, Vdup1
Target/Specificity:
This Mouse Txnip antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-145 amino acids from the Central region of mouse Txnip.
Antigen Region:
116-145
Antigen Type: Synthetic Peptide
Gene Name: Txnip
Gene ID: 56338
Primary Accession: Q8BG60
NCBI Accession: NP_001009935.1;NP_076208.2
Other Accession: Q5M7W1; NP_001009935.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
|---|
Write Your Own Review