Mouse Wnk3 Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP16164b
Background:
WNK3 (WNK lysine deficient protein kinase 3) belongs to the serine/threonine protein kinase family. It lacks the almost invariant catalytic lysine in subdomain II, which is important for binding ATP in the catalytic site. A conserved lysine in subdomain I is thought to provide this function. WNK3 activates Na-(K)-Cl cotransporters by increasing their phosphorylation and appears to be a crucial component of the kinase/phosphatase signaling pathway that coordinately regulates the Cl? influx and efflux branches of the SLC12A cotransporter family.
Other Names:
Serine/threonine-protein kinase WNK3, Protein kinase lysine-deficient 3, Protein kinase with no lysine 3, Wnk3
Gene Name: Wnk3 {ECO:0000312|MGI:MGI:2652875}
Gene ID: 279561
Primary Accession: Q80XP9
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
WNK3 (WNK lysine deficient protein kinase 3) belongs to the serine/threonine protein kinase family. It lacks the almost invariant catalytic lysine in subdomain II, which is important for binding ATP in the catalytic site. A conserved lysine in subdomain I is thought to provide this function. WNK3 activates Na-(K)-Cl cotransporters by increasing their phosphorylation and appears to be a crucial component of the kinase/phosphatase signaling pathway that coordinately regulates the Cl? influx and efflux branches of the SLC12A cotransporter family.
Other Names:
Serine/threonine-protein kinase WNK3, Protein kinase lysine-deficient 3, Protein kinase with no lysine 3, Wnk3
Gene Name: Wnk3 {ECO:0000312|MGI:MGI:2652875}
Gene ID: 279561
Primary Accession: Q80XP9
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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