MR1 Polyclonal Antibody

Background:
MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome.

Research Area: Immunology

Synonyms:
Class I histocompatibility antigen like protein, Class I histocompatibility antigen-like protein, HLALS, HMR1, Major histocompatibility complex class I like sequence, Major histocompatibility complex class I related, Major histocompatibility complex class I related gene protein, Major histocompatibility complex class I related isoform CRA a, Major histocompatibility complex class I related isoform CRA c, Major histocompatibility complex class I related isoform CRA d, Major histocompatibility complex class I-related gene protein, MHC class I like antigen MR 1, MHC class I like antigen MR1, MHC class I related gene protein, MHC class I related protein 1 isoform B, MHC class I related protein 1 isoform C, MHC class I-related gene protein, MR 1, Mr1, Mr1 protein, MR1B, MR1C

Immunogen: Fusion protein of human MR1

Swissprot: Q95460
Gene Accession: BC012485

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.32 mg/mL
Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.