MR1 polyclonal (C-term), anti-human
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In stock
SKU
AC-AP17332B
Catalog Number: AC-AP17332B
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB37199
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB37199
Applications: WB
Datasheet
Request Information
Background:
MR1 has antigen presentation function. Involved in the development and expansion of a small population of T cells expressing an invariant T cell receptor alpha chain called mucosal-associated invariant T cells (MAIT). MAIT cells are preferentially located in the gut lamina propria and therfore may be involed in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent.
Other Names:
Major histocompatibility complex class I-related gene protein, MHC class I-related gene protein, Class I histocompatibility antigen-like protein, MR1
Target/Specificity:
This MR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 312-341 amino acids from the C-terminal region of human MR1.
Antigen Region:
312-341
Antigen Type: Synthetic Peptide
Gene Name: MR1
Gene ID: 3140
Primary Accession: Q95460
NCBI Accession: NP_001181928.1;NP_001181929.1;NP_001181964.1;NP_001522.1
Other Accession: NP_001181929.1;NP_001181928.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
MR1 has antigen presentation function. Involved in the development and expansion of a small population of T cells expressing an invariant T cell receptor alpha chain called mucosal-associated invariant T cells (MAIT). MAIT cells are preferentially located in the gut lamina propria and therfore may be involed in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent.
Other Names:
Major histocompatibility complex class I-related gene protein, MHC class I-related gene protein, Class I histocompatibility antigen-like protein, MR1
Target/Specificity:
This MR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 312-341 amino acids from the C-terminal region of human MR1.
Antigen Region:
312-341
Antigen Type: Synthetic Peptide
Gene Name: MR1
Gene ID: 3140
Primary Accession: Q95460
NCBI Accession: NP_001181928.1;NP_001181929.1;NP_001181964.1;NP_001522.1
Other Accession: NP_001181929.1;NP_001181928.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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