MRE11A antibody (clone 1D8-A6), anti-human
€435.00
In stock
SKU
AC-AT2901a
Catalog Number: AC-AT2901a
Size: 100 µg
Isotype: mouse IgG2a kappa
Applications: WB
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Size: 100 µg
Isotype: mouse IgG2a kappa
Applications: WB
Request Information AC-AT2901a">Request Information
Background:
This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Other Names:
Double-strand break repair protein MRE11A, Meiotic recombination 11 homolog 1, MRE11 homolog 1, Meiotic recombination 11 homolog A, MRE11 homolog A, MRE11A, HNGS1, MRE11
Antigen Type:
Recombinant Protein
Gene Name: MRE11 {ECO:0000303|PubMed:8530104, ECO:0000312|HGNC:HGNC:7230}
Gene ID: 4361
NCBI Accession: NP_005581.2;NP_005582.1
Primary Accession: P49959
Other Accession: BC005241
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Other Names:
Double-strand break repair protein MRE11A, Meiotic recombination 11 homolog 1, MRE11 homolog 1, Meiotic recombination 11 homolog A, MRE11 homolog A, MRE11A, HNGS1, MRE11
Antigen Type:
Recombinant Protein
Gene Name: MRE11 {ECO:0000303|PubMed:8530104, ECO:0000312|HGNC:HGNC:7230}
Gene ID: 4361
NCBI Accession: NP_005581.2;NP_005582.1
Primary Accession: P49959
Other Accession: BC005241
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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