MRE11A polyclonal, anti-human, mouse
€295.00
In stock
SKU
K003418P
Catalog Number: K003418P
Size: 100 μl
Other size: 50 μl
Isotype: Rabbit IgG
Applications: WB, IP
Request Manual
Questions? Contact us!
Size: 100 μl
Other size: 50 μl
Isotype: Rabbit IgG
Applications: WB, IP
Request Manual
Questions? Contact us!
Background:
This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Synonyms: MRE11, MRE11A, ATLD, HNGS1, MRE11B,
Cellular Location: Nucleus
Immunogen:
Recombinant protein of human MRE11A
Gene Symbol: MRE11A
Gene ID: 4361
Swiss prot: P49959
Calculated MW: 81kDa
Recommended dilution:
WB 1:500-2000, IP 1:50-100,
Purity:
Affinity purification
Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at -20℃. Avoid freeze / thaw cycles.
This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Synonyms: MRE11, MRE11A, ATLD, HNGS1, MRE11B,
Cellular Location: Nucleus
Immunogen:
Recombinant protein of human MRE11A
Gene Symbol: MRE11A
Gene ID: 4361
Swiss prot: P49959
Calculated MW: 81kDa
Recommended dilution:
WB 1:500-2000, IP 1:50-100,
Purity:
Affinity purification
Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at -20℃. Avoid freeze / thaw cycles.
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