MRGPRX1 Polyclonal Antibody

Background:
MRGX1 is an opiod receptor that has been reported exclusively in dorsal root ganglion. MRGX1 is probably involved in the function of nociceptive neurons and may regulate nociceptor function and/or development, including the sensation or modulation of pain. It is potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells.

Research Area: Signal transduction

Synonyms:
GPCR, MAS related gene MRGX1, MAS related GPR member X1, MRGPRX1, MRGX1, SNSR4

Immunogen: Synthetic peptide of human MRGPRX1

Swissprot: Q96LB2
Gene Accession: NP_671732

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.5 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.