MRGPRX1 Polyclonal Antibody

Background:
MRGX1 is an opiod receptor that has been reported exclusively in dorsal root ganglion. MRGX1 is probably involved in the function of nociceptive neurons and may regulate nociceptor function and/or development, including the sensation or modulation of pain. It is potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells.

Research Area: Signal transduction

Synonyms:
MRGPRX1, GPCR, MGRG2, MRGX1, SNSR4

Immunogen: Recombinant fusion protein of human MRGPRX1 (NP_671732.3).

Swissprot: Q96LB2
Gene ID: 259249

Calculated MW: 36 kDa
Observed MW: 36 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.