MRGPRX2 polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP16522b
Catalog Number: AC-AP16522b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36019
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36019
Applications: WB
Datasheet
Request Information
Background:
MRGPRX2 is the orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca(2+) but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled.
Other Names:
Mas-related G-protein coupled receptor member X2, MRGPRX2, MRGX2
Target/Specificity:
This MRGPRX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 287-315 amino acids from the C-terminal region of human MRGPRX2.
Antigen Region:
287-315
Antigen Type: Synthetic Peptide
Gene Name: MRGPRX2
Gene ID: 117194
Primary Accession: Q96LB1
NCBI Accession: NP_473371.1
Other Accession: NP_473371.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
MRGPRX2 is the orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca(2+) but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled.
Other Names:
Mas-related G-protein coupled receptor member X2, MRGPRX2, MRGX2
Target/Specificity:
This MRGPRX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 287-315 amino acids from the C-terminal region of human MRGPRX2.
Antigen Region:
287-315
Antigen Type: Synthetic Peptide
Gene Name: MRGPRX2
Gene ID: 117194
Primary Accession: Q96LB1
NCBI Accession: NP_473371.1
Other Accession: NP_473371.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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