MRI1 polyclonal, anti-human, mouse, rat

Background:
This enzyme functions in the methionine salvage pathway by catalyzing the interconversion of methylthioribose-1-phosphate and methythioribulose-1-phosphate. Elevated expression of the encoded protein is associated with metastatic melanoma and this protein promotes melanoma cell invasion independent of its enzymatic activity. Mutations in this gene may be associated with vanishing white matter disease (VMWD).

Alternative Name:
M1Pi, MRDI, MTNA, Ypr118w

Application Dilution: WB: 1:500 - 1:2000

Specificity: MRI1 polyclonal antibody detects endogenous levels of MRI1 protein.

Immunogen:
Recombinant protein of human MRI1

MW: 45kDa

Swis Prot.: Q9BV20

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.