MRM3 Polyclonal Antibody

Background:
Efficient translation of mitochondrial-derived transcripts requires proper assembly of the large subunit of the mitochondrial ribosome. Central to the biogenesis of this large subunit is the A-loop of mitochondrial 16S rRNA, which is modified by three rRNA methyltransferases located near mtDNA nucleoids. The protein encoded by this gene methylates G(1370) of 16S rRNA, and this modification is necessary for proper ribosomal large subnit assembly. Two transcript variants encoding different isoforms have been found for this gene.

Research Area: Epigenetics and Nuclear Signaling

Synonyms:
MRM3, RMTL1, RNMTL1

Immunogen: Recombinant fusion protein of human MRM3 (NP_060616.1).

Swissprot: Q9HC36
Gene ID: 55178

Calculated MW: 47 kDa
Observed MW: 47 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.