MRP-L22 Polyclonal Antibody

Background:
mitochondrial ribosomal protein L22(MRPL22) Homo sapiens Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for this gene. [provide

Alternative Names:
MRPL22, MRPL25, RPML25, HSPC158, 39S ribosomal protein L22, mitochondrial, L22mt, MRP-L22, 39S ribosomal protein L25, mitochondrial, L25mt, MRP-L25

Immunogen: The antiserum was produced against synthesized peptide derived from human MRPL22. AA range:91-140

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 24

GeneID: MRPL22

Storage: -20°C/1 year

NOTE: For Research Use Only