MRP-S24 polyclonal antibody, anti-human, mouse, rat

Background:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPS24 (mitochondrial ribosomal protein S24) encodes a 28S subunit protein. A pseudogene corresponding to MRPS24 is found on chromosome 11. Read-through transcription exists between MRPS24 and the upstream upregulator of cell proliferation (URGCP) gene.

Research Area: Others

Synonyms: MRPS24, HSPC335, 28S ribosomal protein S24, mitochondrial, MRP-S24, S24mt, bMRP-47, bMRP47

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year