MRP-S36 (V36) polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS3881
Background:
Mitochondrial ribosomes consist of a large 39S subunit and a small 28S subunit, both of which are comprised of multiple mitochondrial ribosomal proteins (MRPs) that are encoded by nuclear genes and are essential for protein synthesis within mitochondria. MRP-S36 (mitochondrial ribosomal protein S36), is a 103 amino acid protein that localizes to the mitochondrion, where it exists as a component of the 28S ribosomal subunit and works in conjunction with other MRPs to mediate protein synthesis. The gene encoding MRP-S36 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
Alternative Name:
28S ribosomal protein S36, mitochondrial, MRP-S36, S36mt, MRPS36, ORF Names: DC47
Application Dilution: IHC: 1:50~1:200
Specificity: MRP-S36 (V36) polyclonal antibody detects endogenous levels of MRP-S36 protein.
Immunogen:
Synthetic peptide, corresponding to the N-terminal of Human MRP-S36.
MW: ~ 15 kDa
Swis Prot.: P82909
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Mitochondrial ribosomes consist of a large 39S subunit and a small 28S subunit, both of which are comprised of multiple mitochondrial ribosomal proteins (MRPs) that are encoded by nuclear genes and are essential for protein synthesis within mitochondria. MRP-S36 (mitochondrial ribosomal protein S36), is a 103 amino acid protein that localizes to the mitochondrion, where it exists as a component of the 28S ribosomal subunit and works in conjunction with other MRPs to mediate protein synthesis. The gene encoding MRP-S36 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
Alternative Name:
28S ribosomal protein S36, mitochondrial, MRP-S36, S36mt, MRPS36, ORF Names: DC47
Application Dilution: IHC: 1:50~1:200
Specificity: MRP-S36 (V36) polyclonal antibody detects endogenous levels of MRP-S36 protein.
Immunogen:
Synthetic peptide, corresponding to the N-terminal of Human MRP-S36.
MW: ~ 15 kDa
Swis Prot.: P82909
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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