MRPL1 Polyclonal Antibody

Background:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L1 ribosomal protein family.

Research Area: Epigenetics and Nuclear Signaling, Metabolism

Synonyms:
39S ribosomal protein L1, 39S ribosomal protein L1, mitochondrial precursor , BM022 , L1mt, mitochondrial, Mitochondrial ribosomal protein L1, MRP L1, MRP-L1, Mrpl1, RM01

Immunogen: Fusion protein of human MRPL1

Swissprot: Q9BYD6
Gene Accession: BC014356

Calculated MW: 37 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.84 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.