MRPL10 polyclonal, anti-human
€305.00
In stock
SKU
BS61591
Background:
Mitochondria have their own translation machinery for production of 13 proteins that are required for oxidative phosphorylation. MRP-L10 (39S ribosomal protein L10, mitochondrial), also known as MRPL8, is a 261 amino acid protein that is a component of the large ribosomal subunit of the mitochondria. MRP-L10 is one of the 70 protein components of mitochondrial ribosomes that are encoded by the nuclear genome. MRP-L10 is deacteylated in a NAD+- dependent manner by SIRT3, which is an event that contributes to the regulation of mitochondrial protein synthesis. The gene encoding MRP-L10 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1.
Alternative Name:
39S ribosomal protein L10, mitochondrial, L10mt, MRP-L10, 39S ribosomal protein L8, mitochondrial, L8mt, MRP-L8
Application Dilution: WB: 1:500~1:1000
Specificity: MRPL10 polyclonal antibody detects endogenous levels of MRPL10 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 215-259 of Human MRPL10.
MW: ~ 29 kDa
Swis Prot.: Q7Z7H8
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 96% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Mitochondria have their own translation machinery for production of 13 proteins that are required for oxidative phosphorylation. MRP-L10 (39S ribosomal protein L10, mitochondrial), also known as MRPL8, is a 261 amino acid protein that is a component of the large ribosomal subunit of the mitochondria. MRP-L10 is one of the 70 protein components of mitochondrial ribosomes that are encoded by the nuclear genome. MRP-L10 is deacteylated in a NAD+- dependent manner by SIRT3, which is an event that contributes to the regulation of mitochondrial protein synthesis. The gene encoding MRP-L10 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1.
Alternative Name:
39S ribosomal protein L10, mitochondrial, L10mt, MRP-L10, 39S ribosomal protein L8, mitochondrial, L8mt, MRP-L8
Application Dilution: WB: 1:500~1:1000
Specificity: MRPL10 polyclonal antibody detects endogenous levels of MRPL10 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 215-259 of Human MRPL10.
MW: ~ 29 kDa
Swis Prot.: Q7Z7H8
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 96% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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