MRPL12 antibody (clone 3B12-1A3), anti-human
€435.00
In stock
SKU
AC-AT2902a
Catalog Number: AC-AT2902a
Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, IHC, IF, E
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Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, IHC, IF, E
Request Information AC-AT2902a">Request Information
Background:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which forms homodimers. In prokaryotic ribosomes, two L7/L12 dimers and one L10 protein form the L8 protein complex.
Other Names:
39S ribosomal protein L12, mitochondrial, L12mt, MRP-L12, 5c5-2, MRPL12, RPML12
Antigen Type:
Recombinant Protein
Gene Name: MRPL12
Gene ID: 6182
NCBI Accession: NP_002940.2
Primary Accession: P52815
Other Accession: BC002344
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which forms homodimers. In prokaryotic ribosomes, two L7/L12 dimers and one L10 protein form the L8 protein complex.
Other Names:
39S ribosomal protein L12, mitochondrial, L12mt, MRP-L12, 5c5-2, MRPL12, RPML12
Antigen Type:
Recombinant Protein
Gene Name: MRPL12
Gene ID: 6182
NCBI Accession: NP_002940.2
Primary Accession: P52815
Other Accession: BC002344
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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