MRPL28 Polyclonal Antibody

Background:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
39S ribosomal protein L28, 39S ribosomal protein L28 mitochondrial, 39S ribosomal protein L28 mitochondrial precursor, HGNC6756, L28mt, MAAT 1, MAAT1, Melanoma antigen p15, Melanoma associated antigen recognised by cytotoxic T lymphocytes, Melanoma associated antigen recognized by T lymphocytes, Melanoma-associated antigen recognized by T-lymphocytes, MGC8499, mitochondrial, Mitochondrial ribosomal protein L28, MRP L28, MRP-L28, MRPL 28, mrpl28, P15, RM28

Immunogen: Recombinant protein of human MRPL28

Swissprot: Q13084
Gene Accession: BC000990

Calculated MW: 30 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.6 mg/mL
Dilution: WB 1:1000-1:5000, IHC 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-55683/sc-55684/sc-55685/sc-292181