MRPL32 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS61602
Background:
Mitochondrial ribosomes consist of a large 39S subunit and a small 28S subunit, both of which are comprised of multiple mitochondrial ribosomal proteins (MRPs) that are encoded by nuclear genes and are essential for protein synthesis within mitochondria. MRP-L32 (mitochondrial ribosomal protein L32), also known as HSPC283, is a 188 amino acid protein that localizes to the mitochondrion, where it exists as a component of the 39S ribosomal subunit and works in conjunction with other MRPs to mediate protein synthesis. The gene encoding MRP-L32 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
Alternative Name:
39S ribosomal protein L32, mitochondrial, L32mt, MRP-L32
Application Dilution: WB: 1:500~1:1000
Specificity: MRPL32 polyclonal antibody detects endogenous levels of MRPL32 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 105-149 of Human MRPL32.
MW: ~ 25 kDa
Swis Prot.: Q9BYC8
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 107% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Mitochondrial ribosomes consist of a large 39S subunit and a small 28S subunit, both of which are comprised of multiple mitochondrial ribosomal proteins (MRPs) that are encoded by nuclear genes and are essential for protein synthesis within mitochondria. MRP-L32 (mitochondrial ribosomal protein L32), also known as HSPC283, is a 188 amino acid protein that localizes to the mitochondrion, where it exists as a component of the 39S ribosomal subunit and works in conjunction with other MRPs to mediate protein synthesis. The gene encoding MRP-L32 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
Alternative Name:
39S ribosomal protein L32, mitochondrial, L32mt, MRP-L32
Application Dilution: WB: 1:500~1:1000
Specificity: MRPL32 polyclonal antibody detects endogenous levels of MRPL32 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 105-149 of Human MRPL32.
MW: ~ 25 kDa
Swis Prot.: Q9BYC8
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 107% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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