MRPS15 polyclonal (Center), anti-human

MRPS15 polyclonal (Center), anti-human

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In stock
SKU
AC-AP16498c
Catalog Number: AC-AP16498c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB35888
Applications: WB
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Background:
Mammalian mitochondrial ribosomal proteins are encoded bynuclear genes and help in protein synthesis within themitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of asmall 28S subunit and a large 39S subunit. They have an estimated75% protein to rRNA composition compared to prokaryotic ribosomes,where this ratio is reversed. Another difference between mammalianmitoribosomes and prokaryotic ribosomes is that the latter containa 5S rRNA. Among different species, the proteins comprising themitoribosome differ greatly in sequence, and sometimes inbiochemical properties, which prevents easy recognition by sequencehomology. This gene encodes a 28S subunit protein that belongs tothe ribosomal protein S15P family. The encoded protein is more thantwo times the size of its E. coli counterpart, with the 12S rRNAbinding sites conserved. Between human and mouse, the encodedprotein is the least conserved among small subunit ribosomalproteins. Pseudogenes corresponding to this gene are found onchromosomes 15q and 19q.

Other Names:
28S ribosomal protein S15, mitochondrial, MRP-S15, S15mt, MRPS15, RPMS15

Target/Specificity:
This MRPS15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124-153 amino acids from the Central region of human MRPS15.

Antigen Region:
124-153

Antigen Type: Synthetic Peptide

Gene Name: MRPS15
Gene ID: 64960
Primary Accession: P82914
NCBI Accession: NP_112570.2
Other Accession: NP_112570.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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