MRPS18C Polyclonal Antibody

Background:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology.

Research Area: Epigenetics and Nuclear Signaling

Synonyms:
28S ribosomal protein S18 1, mitochondrial, 28S ribosomal protein S18-1, 28S ribosomal protein S18c, 28S ribosomal protein S18c mitochondrial, CGI-134, mitochondrial, Mitochondrial ribosomal protein S18 1, Mitochondrial ribosomal protein S18C, MRP-S18-1, MRP-S18-c, MRPS18 1, Mrps18-c, Mrps18c, RT18C, S18mt-c

Immunogen: Full length fusion protein

Swissprot: Q9Y3D5
Gene Accession: BC005186

Calculated MW: 16 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.4 mg/mL
Dilution: WB 1:500-1:2000, ELISA 1:2000-1:5000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.