MRPS35 Polyclonal Antibody

Background:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that has had confusing nomenclature in the literature. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Pseudogenes corresponding to this gene are found on chromosomes 3p, 5q, and 10q. MRPS35 (Mitochondrial Ribosomal Protein S35) is a Protein Coding gene. Among its related pathways are Mitochondrial translation and Organelle biogenesis and maintenance. GO annotations related to this gene include poly(A) RNA binding and structural constituent of ribosome.

Research Area: Epigenetics and Nuclear Signaling, Metabolism

Synonyms:
28S ribosomal protein S28, 28S ribosomal protein S28, mitochondrial, 28S ribosomal protein S35, 28S ribosomal protein S35 mitochondrial precursor, 28S ribosomal protein S35, mitochondrial, DKFZp762P093, HDCMD11P, MDS023, MGC104278, mitochondrial, Mitochondrial ribosomal protein S28, Mitochondrial ribosomal protein S35, MRP S28, MRP S35, MRP-S28, MRP-S35, MRPS 28, MRPS 35, MRPS28, MRPS35, OTTHUMP00000240420, OTTHUMP00000240422, OTTHUMP00000240424, PSEC0213, RT35, S28mt, S35mt

Immunogen: Fusion protein of human MRPS35

Swissprot: P82673
Gene Accession: BC015862

Calculated MW: 37 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.96 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.