MS4A2 antibody (clone 3B1), anti-human
€435.00
In stock
SKU
AC-AT2909a
Catalog Number: AC-AT2909a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
Request Information AC-AT2909a">Request Information
Background:
The allergic response involves the binding of allergen to receptor-bound IgE followed by cell activation and the release of mediators responsible for the manifestations of allergy. The IgE-receptor, a tetramer composed of an alpha, beta, and 2 disulfide-linked gamma chains, is found on the surface of mast cells and basophils. This gene encodes the beta subunit of the high affinity IgE receptor which is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member is localized to 11q12, among a cluster of family members.
Other Names:
High affinity immunoglobulin epsilon receptor subunit beta, FcERI, Fc epsilon receptor I beta-chain, IgE Fc receptor subunit beta, Membrane-spanning 4-domains subfamily A member 2, MS4A2, APY, FCER1B, IGER
Antigen Type:
Recombinant Protein
Gene Name: MS4A2
Gene ID: 2206
NCBI Accession: NP_000130.1
Primary Accession: Q01362
Other Accession: NM_000139
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The allergic response involves the binding of allergen to receptor-bound IgE followed by cell activation and the release of mediators responsible for the manifestations of allergy. The IgE-receptor, a tetramer composed of an alpha, beta, and 2 disulfide-linked gamma chains, is found on the surface of mast cells and basophils. This gene encodes the beta subunit of the high affinity IgE receptor which is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member is localized to 11q12, among a cluster of family members.
Other Names:
High affinity immunoglobulin epsilon receptor subunit beta, FcERI, Fc epsilon receptor I beta-chain, IgE Fc receptor subunit beta, Membrane-spanning 4-domains subfamily A member 2, MS4A2, APY, FCER1B, IGER
Antigen Type:
Recombinant Protein
Gene Name: MS4A2
Gene ID: 2206
NCBI Accession: NP_000130.1
Primary Accession: Q01362
Other Accession: NM_000139
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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