MSH2 (clone 1B3=3A2B8C), anti-human, monkey

Protein Family: Enzymes

Pathway and Disease: Cancers, Replication and Repair

Description:
MSH2 (DNA mismatch repair protein Msh2) is a component of the post-replicative DNA mismatch repair system (MMR). MSH2 forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) that bind to DNA mismatches and initiate DNA repair. Defects in MSH2 are the cause of hereditary nonpolyposis colorectal cancer type 1 and endometrial cancers.

Alternate Names: DNA mismatch repair protein Msh2, MutS protein homolog 2, MSH2

Application Notes: WB: 1: 500-1: 2,000, IHC: 1: 200-1: 1,000, IF: 1: 200-1: 1,000

Accession No.: P43246, NP_000242

Antigen: Purified recombinant fragment of human MSH2 expressed in E. coli.

Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.