MSH2 (clone 4D1G12), anti-

Background:
This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

Research Area: Epigenetics and Nuclear Signaling

Synonyms: FCC1, COCA1, HNPCC, LCFS2, hMSH2, HNPCC1

Immunogen: Purified recombinant fragment of human MSH2 (AA: 2-151) expressed in E. Coli.

Formulation: Purified antibody in PBS with 0.05% sodium azide

Storage:
4°C|-20°C for long term storage