MSH2 Peptide
€100.00
In stock
SKU
350528
Protein Family: Enzymes
Pathway and Disease: Cancers, Replication and Repair
Alternate Names: DNA mismatch repair protein Msh2; MutS protein homolog 2; MSH2
Accession No.: P43246, NP_000242
Description:
DNA mismatch repair protein Msh2 (MSH2) is a component of the post-replicative DNA mismatch repair system (MMR). MSH2 forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) that bind to DNA mismatches and initiate DNA repair. Defects in MSH2 are the cause of hereditary non-polyposis colorectal cancer type 1 and endometrial cancers.
Format:
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
MW: 2001.4 g/mol
Sequence:
The synthetic peptide used to raise the antibody Cat. No. 200166 is selected from a sequence within the C-term region of human MSH2. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Composition:
C87H157N25O26S1
Purity:
> 80% by HPLC
Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Pathway and Disease: Cancers, Replication and Repair
Alternate Names: DNA mismatch repair protein Msh2; MutS protein homolog 2; MSH2
Accession No.: P43246, NP_000242
Description:
DNA mismatch repair protein Msh2 (MSH2) is a component of the post-replicative DNA mismatch repair system (MMR). MSH2 forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) that bind to DNA mismatches and initiate DNA repair. Defects in MSH2 are the cause of hereditary non-polyposis colorectal cancer type 1 and endometrial cancers.
Format:
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
MW: 2001.4 g/mol
Sequence:
The synthetic peptide used to raise the antibody Cat. No. 200166 is selected from a sequence within the C-term region of human MSH2. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Composition:
C87H157N25O26S1
Purity:
> 80% by HPLC
Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
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