MSH2 polyclonal, anti-human, mouse, rat antibody
€275.00
In stock
SKU
AC-ABV10313-100
Catalog Number: AC-ABV10313-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB, IHC, IP
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB, IHC, IP
Datasheet
Request Information
Background:
DNA mismatch repair genes have been found to be associated with hereditary nonpolyposis colorectal cancer (HNPCC). Inherited mutations in the MSH2 were demonstrated at high frequency in HNPCC and were shown to be associated with microsatellite instability. The demonstration that 10 to 45% of pancreatic, gastric, breast, ovarian and small cell lung cancers also display microsatellite instability s µggests that DNA mismatch repair is not restricted to HNPCC tumors but is a common feature in tumor initiation or progression.
Other Names:
HNPCC , COCA1 , Flow cytometryC1 , HNPCC1 , BAT-26 , Familial Nonpolyposis Colon Cancer Type 1 , Colorectal Cancer Type 1
Primary Accession: P43246
Gene Name: MSH2
Gene ID: 4436
Concentration (mg/ml): 0.2 mg/ml
DNA mismatch repair genes have been found to be associated with hereditary nonpolyposis colorectal cancer (HNPCC). Inherited mutations in the MSH2 were demonstrated at high frequency in HNPCC and were shown to be associated with microsatellite instability. The demonstration that 10 to 45% of pancreatic, gastric, breast, ovarian and small cell lung cancers also display microsatellite instability s µggests that DNA mismatch repair is not restricted to HNPCC tumors but is a common feature in tumor initiation or progression.
Other Names:
HNPCC , COCA1 , Flow cytometryC1 , HNPCC1 , BAT-26 , Familial Nonpolyposis Colon Cancer Type 1 , Colorectal Cancer Type 1
Primary Accession: P43246
Gene Name: MSH2
Gene ID: 4436
Concentration (mg/ml): 0.2 mg/ml
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