MSH2 polyclonal, anti-human, mouse, rat

Background:
This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

Synonyms: COCA1, FCC1, HNPCC, HNPCC1, LCFS2

Cellular Location: Nucleus

Immunogen:
Recombinant protein of human MSH2

Gene Symbol: MSH2

Gene ID: 4436

Swiss prot: P43246

Calculated MW: 105kDa

Recommended dilution:
WB 1:500-2000, IP 1:20-50,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.