MSH2 polyclonal (Center), anti-human

Background:
MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. [provided by RefSeq].

Other Names:
DNA mismatch repair protein Msh2, hMSH2, MutS protein homolog 2, MSH2

Target/Specificity:
This MSH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 637-665 amino acids from the Central region of human MSH2.

Antigen Region:
637-665

Antigen Type: Synthetic Peptide

Gene Name: MSH2
Gene ID: 4436
Primary Accession: P43246
NCBI Accession: NP_000242.1;NP_001245210.1
Other Accession: NP_000242.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.