MSRB2 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS71186
Background:
MsrB2 (methionine sulfoxide reductase B2), also known as CBS1, MSRB, PILB, CBS-1 or CGI-131, is a 182 amino acid mitochondrial protein that is ubiquitously expressed. Belonging to the MsrB Met sulfoxide reductase family, MsrB2 acts as a catalyst for the reduction of free and protein-bound methionine sulfoxide to methionine. Upon oxidative stress, MsrB2 is suggested to play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance. MsrB2 utilizes zinc ions, one per subunit, as cofactors.
Alternative Name:
CBS1, MSRB, PILB, CBS-1, CGI-131,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: MSRB2 polyclonal antibody detects endogenous levels of MSRB2 protein.
Immunogen:
Recombinant protein of human MSRB2.
MW: ~ 20 kDa
Swis Prot.: Q9Y3D2
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
MsrB2 (methionine sulfoxide reductase B2), also known as CBS1, MSRB, PILB, CBS-1 or CGI-131, is a 182 amino acid mitochondrial protein that is ubiquitously expressed. Belonging to the MsrB Met sulfoxide reductase family, MsrB2 acts as a catalyst for the reduction of free and protein-bound methionine sulfoxide to methionine. Upon oxidative stress, MsrB2 is suggested to play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance. MsrB2 utilizes zinc ions, one per subunit, as cofactors.
Alternative Name:
CBS1, MSRB, PILB, CBS-1, CGI-131,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: MSRB2 polyclonal antibody detects endogenous levels of MSRB2 protein.
Immunogen:
Recombinant protein of human MSRB2.
MW: ~ 20 kDa
Swis Prot.: Q9Y3D2
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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