MST1 polyclonal (C-term), anti-human

MST1 polyclonal (C-term), anti-human

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In stock
SKU
AC-AP7922a
Catalog Number: AC-AP7922a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB1193
Applications: IHC-P, WB
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Background:
MST1 is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it is possible that this protein induces the chromatin condensation observed in this process.

Other Names:
Serine/threonine-protein kinase 4, Mammalian STE20-like protein kinase 1, MST-1, STE20-like kinase MST1, Serine/threonine-protein kinase Krs-2, Serine/threonine-protein kinase 4 37kDa subunit, MST1/N, Serine/threonine-protein kinase 4 18kDa subunit, MST1/C, STK4, KRS2, MST1

Target/Specificity:
This MST1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 385-415 amino acids from the C-terminal region of human MST1.

Antigen Region:
385-415

Antigen Type: Synthetic Peptide

Gene Name: STK4 (HGNC:11408)
Gene ID: 6789
Primary Accession: Q13043
NCBI Accession: NP_006273.1
Other Accession: Q5E9L6
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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