MST3 polyclonal (C-term), anti-human

MST3 polyclonal (C-term), anti-human

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In stock
SKU
AC-AP7924a
Catalog Number: AC-AP7924a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB1197-1198
Applications: WB, IHC-P
Datasheet

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Background:
The yeast 'Sterile 20' gene (STE20) functions upstream of the mitogen-activated protein kinase (MAPK) cascade. In mammals, protein kinases related to STE20 can be divided into 2 subfamilies based on their structure and regulation. Members of the PAK subfamily (see PAK3; MIM 300142) contain a C-terminal catalytic domain and an N-terminal regulatory domain that has a CDC42 (MIM 116952)-binding domain. In contrast, members of the GCK subfamily (see MAP4K2; MIM 603166), also called the Sps1 subfamily, have an N-terminal catalytic domain and a C-terminal regulatory domain without a CDC42-binding domain. STK24 belongs to the GCK subfamily of STE20-like kinases (Zhou et al., 2000 [PubMed 10644707]).[supplied by OMIM]

Other Names:
Serine/threonine-protein kinase 24, Mammalian STE20-like protein kinase 3, MST-3, STE20-like kinase MST3, Serine/threonine-protein kinase 24 36 kDa subunit, Mammalian STE20-like protein kinase 3 N-terminal, MST3/N, Serine/threonine-protein kinase 24 12 kDa subunit, Mammalian STE20-like protein kinase 3 C-terminal, MST3/C, STK24, MST3, STK3

Target/Specificity:
This MST3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 345-374 amino acids from the C-terminal region of human MST3.

Antigen Region:
345-374

Antigen Type: Synthetic Peptide

Gene Name: STK24 (HGNC:11403)
Gene ID: 8428
Primary Accession: Q9Y6E0
NCBI Accession: NP_001027467.2;NP_003567.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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