MSTN Polyclonal Antibody

Background:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals.

Research Area: Cancer, Signal Transduction

Synonyms:
MSTN, GDF8, MSLHP, myostatin

Immunogen: Recombinant fusion protein of human MSTN (NP_005250.1).

Swissprot: O14793
Gene ID: 2660

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "IHC 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.