Msx2 Antibody (N-term) Blocking Peptide

Background:
Msx2 is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. This protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in the Msx2 gene are associated with parietal foramina 1 and craniosynostosis type 2.

Other Names:
Homeobox protein MSX-2, Homeobox protein Hox-8, MSX2, HOX8

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2709a was selected from the N-term region of human Msx2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Gene Name: MSX2

Gene ID: 4488
Primary Accession: P35548
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.