MT-ATP8 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60106
Background:
Mitochondrial ATP synthase is composed of two multi-subunit complexes that utilize an inner membrane electrochemical gradient to catalyze the synthesis of ATP during oxidative phosphorylation. The two multi-subunit complexes are designated F1 and F0, the former of which comprises the soluble catalytic core and the latter of which comprises the membrane-spanning proton channel of ATP synthase. ATP8, also known as MT-ATP8, ATPASE8 or MTATP8, is a 68 amino acid single-pass membrane protein that localizes to mitochondria and functions as a minor subunit of the F0 complex. The gene encoding ATP8 maps to the mitochondrial chromosome and may be involved in the pathogenesis of multiple sclerosis.
Alternative Name:
ATP synthase protein 8, A6L, F-ATPase subunit 8, MT-ATP8, ATP8, ATPASE8, MTATP8
Application Dilution: WB: 1:500~1:1000
Specificity: MT-ATP8 polyclonal antibody detects endogenous levels of MT-ATP8 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human MT-ATP8.
MW: ~ 8 kDa
Swis Prot.: P03928
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Mitochondrial ATP synthase is composed of two multi-subunit complexes that utilize an inner membrane electrochemical gradient to catalyze the synthesis of ATP during oxidative phosphorylation. The two multi-subunit complexes are designated F1 and F0, the former of which comprises the soluble catalytic core and the latter of which comprises the membrane-spanning proton channel of ATP synthase. ATP8, also known as MT-ATP8, ATPASE8 or MTATP8, is a 68 amino acid single-pass membrane protein that localizes to mitochondria and functions as a minor subunit of the F0 complex. The gene encoding ATP8 maps to the mitochondrial chromosome and may be involved in the pathogenesis of multiple sclerosis.
Alternative Name:
ATP synthase protein 8, A6L, F-ATPase subunit 8, MT-ATP8, ATP8, ATPASE8, MTATP8
Application Dilution: WB: 1:500~1:1000
Specificity: MT-ATP8 polyclonal antibody detects endogenous levels of MT-ATP8 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human MT-ATP8.
MW: ~ 8 kDa
Swis Prot.: P03928
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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