MT2A polyclonal, anti-human, mouse
€295.00
In stock
SKU
K008188P
Catalog Number: K008188P
Size: 100 μl
Other size: 50 μl
Isotype: Rabbit IgG
Applications: WB, IHC
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Questions? Contact us!
Size: 100 μl
Other size: 50 μl
Isotype: Rabbit IgG
Applications: WB, IHC
Request Manual
Questions? Contact us!
Background:
This gene is a member of the metallothionein family of genes. Proteins encoded by this gene family are low in molecular weight, are cysteine-rich, lack aromatic residues, and bind divalent heavy metal ions, altering the intracellular concentration of heavy metals in the cell. These proteins act as anti-oxidants, protect against hydroxyl free radicals, are important in homeostatic control of metal in the cell, and play a role in detoxification of heavy metals. The encoded protein interacts with the protein encoded by the homeobox containing 1 gene in some cell types, controlling intracellular zinc levels, affecting apoptotic and autophagy pathways. Some polymorphisms in this gene are associated with an increased risk of cancer.
Synonyms: MT2, MT-2, MT-II
Cellular Location: Cytoplasm
Immunogen:
Recombinant protein of human MT2A
Gene Symbol: MT2A
Gene ID: 4502
Swiss prot: P02795
Calculated MW: 6kDa
Recommended dilution:
WB 1:1000-5000, IHC 1:40-200,
Purity:
Affinity purification
Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
Storage:
Store at -20℃. Avoid freeze / thaw cycles.
This gene is a member of the metallothionein family of genes. Proteins encoded by this gene family are low in molecular weight, are cysteine-rich, lack aromatic residues, and bind divalent heavy metal ions, altering the intracellular concentration of heavy metals in the cell. These proteins act as anti-oxidants, protect against hydroxyl free radicals, are important in homeostatic control of metal in the cell, and play a role in detoxification of heavy metals. The encoded protein interacts with the protein encoded by the homeobox containing 1 gene in some cell types, controlling intracellular zinc levels, affecting apoptotic and autophagy pathways. Some polymorphisms in this gene are associated with an increased risk of cancer.
Synonyms: MT2, MT-2, MT-II
Cellular Location: Cytoplasm
Immunogen:
Recombinant protein of human MT2A
Gene Symbol: MT2A
Gene ID: 4502
Swiss prot: P02795
Calculated MW: 6kDa
Recommended dilution:
WB 1:1000-5000, IHC 1:40-200,
Purity:
Affinity purification
Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
Storage:
Store at -20℃. Avoid freeze / thaw cycles.
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