MT3 Polyclonal Antibody

Background:
Metallothionein (MT) is a sulfhydryl- and cysteine-rich protein found in micro-organisms, plants and all invertebrate and vertebrate animals. Metallothioneins are a group of ubiquitous low-molecular-weight proteins that have functional roles in cell growth, repair and differentiation. Metallothionein are implicated primarily in metal ion detoxification as they are essential for the protection of cells against the toxicity of cadmium, mercury and copper. Metallothioneins are known to be broadly expressed in heart, liver, kidney, breast and testis tissue. Metallothionein 3, also known as MT-3 or GIFB (growth inhibitory factor), is a 68 amino acid protein that belongs to the type 1 family and Metallothionein superfamily. While highly expressed in astrocytes of the normal human brain, Metallothionein 3 expression is reduced in the brains of patients with Alzheimer disease.

Research Area: Cancer, Cell Biology, Metabolism, Neuroscience

Synonyms:
GIF, GIFB, GRIF, Growth inhibitory factor, Metallothionein 3 (growth inhibitory factor (neurotrophic)), Metallothionein 3, Metallothionein III, Metallothionein-3, Metallothionein-III, Mt 3, MT III, MT-3, MT-III, MT3, MT3, ZnMT3

Immunogen: Recombinant protein of human MT3

Swissprot: P25713
Gene Accession: BC013081

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.5 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-164990