MTA1 polyclonal(C-term), anti-human, mouse, rat
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In stock
SKU
AC-AP19705B
Catalog Number: AC-AP19705B
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB40949
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB40949
Applications: WB
Datasheet
Request Information
Background:
This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. [provided by RefSeq].
Other Names:
Metastasis-associated protein MTA1, MTA1
Target/Specificity:
This MTA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 659-687 amino acids from the C-terminal region of human MTA1.
Antigen Region:
659-687
Antigen Type: Synthetic Peptide
Gene Name: MTA1
Gene ID: 9112
Primary Accession: Q13330
NCBI Accession: NP_001190187.1;NP_004680.2
Other Accession: Q62599; Q8K4B0; NP_004680.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. [provided by RefSeq].
Other Names:
Metastasis-associated protein MTA1, MTA1
Target/Specificity:
This MTA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 659-687 amino acids from the C-terminal region of human MTA1.
Antigen Region:
659-687
Antigen Type: Synthetic Peptide
Gene Name: MTA1
Gene ID: 9112
Primary Accession: Q13330
NCBI Accession: NP_001190187.1;NP_004680.2
Other Accession: Q62599; Q8K4B0; NP_004680.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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