MTAP Polyclonal Antibody

Background:
This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown.

Research Area: Cancer, Metabolism, Signal transduction

Synonyms:
MTAP, BDMF, DMSFH, DMSMFH, HEL-249, LGMBF, MSAP, c86fus

Immunogen: Recombinant fusion protein of human MTAP (NP_002442.2).

Swissprot: Q13126
Gene ID: 4507

Calculated MW: 26 kDa/30 kDa/31 kDa/32 kDa/33 kDa/36 kDa/38 kDa
Observed MW: 31 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.