MTBP polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP6657b
Catalog Number: AC-AP6657b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB20020
Applications: FC, WB, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB20020
Applications: FC, WB, IHC-P
Datasheet
Request Information
Background:
MTBP inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells. The protein may play a role in MDM2-dependent TP53/p53 homeostasis in unstressed cells. The protein inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of TP53/p53 and its subsequent degradation.
Other Names:
Mdm2-binding protein, hMTBP, MTBP
Target/Specificity:
This MTBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 853-881 amino acids from the C-terminal region of human MTBP.
Antigen Region:
853-881
Antigen Type: Synthetic Peptide
Gene Name: MTBP
Gene ID: 27085
Primary Accession: Q96DY7
NCBI Accession: NP_071328.2
Other Accession: Q8BJS8
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
MTBP inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells. The protein may play a role in MDM2-dependent TP53/p53 homeostasis in unstressed cells. The protein inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of TP53/p53 and its subsequent degradation.
Other Names:
Mdm2-binding protein, hMTBP, MTBP
Target/Specificity:
This MTBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 853-881 amino acids from the C-terminal region of human MTBP.
Antigen Region:
853-881
Antigen Type: Synthetic Peptide
Gene Name: MTBP
Gene ID: 27085
Primary Accession: Q96DY7
NCBI Accession: NP_071328.2
Other Accession: Q8BJS8
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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