MTCH2 Polyclonal Antibody

Background:
This gene encodes a member of the SLC25 family of nuclear-encoded transporters that are localized in the inner mitochondrial membrane. Members of this superfamily are involved in many metabolic pathways and cell functions. Genome-wide association studies in human have identified single-nucleotide polymorphisms in several loci associated with obesity. This gene is one such locus, which is highly expressed in white adipose tissue and adipocytes, and thought to play a regulatory role in adipocyte differentiation and biology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA can give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon.

Research Area: Cancer, Cell Biology, Metabolism, Signal Transduction

Synonyms:
MTCH2, HSPC032, MIMP, SLC25A50

Immunogen: Recombinant fusion protein of human MTCH2 (NP_055157.1).

Swissprot: Q9Y6C9
Gene ID: 23788

Calculated MW: 33 kDa
Observed MW: 33 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:1000-1:3000 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.