MTF2 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS8693
Background:
MTF-2 (metal response element binding transcription factor 2), also known as PCL2 (polycomb-like protein 2) or metal-response element DNA-binding protein M96, is a 593 amino acid nuclear protein that binds the metal-regulatingelement (MRE) of the gene promoter for Metallothionein 1A. Containing two PHD-type zinc fingers, MTF-2 exists as three alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 1p22.1. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome and houses a large number of diseaseassociated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.
Alternative Name:
Metal-response element-binding transcription factor 2, Metal regulatory transcription factor 2, Metal-response element DNA-binding protein M96, Polycomb-like protein 2, hPCl2, MTF2, PCL2
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: MTF2 polyclonal antibody detects endogenous levels of MTF2 protein.
Immunogen:
Recombinant full length Human MTF2.
MW: ~ 67kDa
Swis Prot.: Q9Y483
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
MTF-2 (metal response element binding transcription factor 2), also known as PCL2 (polycomb-like protein 2) or metal-response element DNA-binding protein M96, is a 593 amino acid nuclear protein that binds the metal-regulatingelement (MRE) of the gene promoter for Metallothionein 1A. Containing two PHD-type zinc fingers, MTF-2 exists as three alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 1p22.1. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome and houses a large number of diseaseassociated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.
Alternative Name:
Metal-response element-binding transcription factor 2, Metal regulatory transcription factor 2, Metal-response element DNA-binding protein M96, Polycomb-like protein 2, hPCl2, MTF2, PCL2
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: MTF2 polyclonal antibody detects endogenous levels of MTF2 protein.
Immunogen:
Recombinant full length Human MTF2.
MW: ~ 67kDa
Swis Prot.: Q9Y483
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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